It started because Game was shittin on Bleek, and Jay had a freestyle that was kinda subliminal in dissing Game, so when Game was in Europe he started talking a lot of shit about Jay. "Ja Rule can suck my dick, Joe Buddens can suck my dick, Jay-Z can suck my dick, etc" Then 50 and Dre had to step in and let Jay know Game had no problem with him until he dissed him on the radio. Game always said he respected Jay a lot, but he wasnt gonna let him diss him no matter how much he liked him. That was over a year ago and the best I remember it.