In my opinion the major problem with all these theories and equations is while they are all about extraterrestial life, or lets call it "other life" for arguments sake, they are still very much all limited by our human earthly existance. They are all theories and equations in relation to what we know.
Why is this a problem? Well humans once knew that the Earth was flat.
The problem is that if we are not cabable of comprehending other forms of life, our equations and best guesses become useless. Its like an ant, with its limited knowledge based in the ant world, trying to comprehend and explain human beings. Its just not possible.
So the only thing all these theories seem to prove right now is that there is no close life form that fits our understanding and can be lableled based apon human understanding. That however does not mean there isnt life on other planets, or even our own planet, which we are just unable to see. If you think this is impossible, remember that there are lots of things around us, waves, particles, etc etc, that we are just unable to see or feel with our limited human senses. But this does not mean that they do not exist.
The same explenation can also be applied to the existance of God, which is why in the first paragraph I said "other life." You have to also consider that their superior technology could be totally different from ours, not based on our physics and hense not recognizable to us.
Basically, we always expect aliens to look different but essentially be the same, in my opinion placeing limitations like that is foolish but at the same time, natrual and ultimatly unavoidable.